Over 400 million people worldwide suffer from diabetes and more than half a million are children below the age of 15 years. A pancreas transplant is a promising solution—placing a functional pancreas into a patient whose pancreas no longer functions properly. However, the amount and quality of available pancreases is limited. Although many artificial pancreases were previously developed by using hydrogels with encapsulated islets, the challenges of low islet encapsulation rate, and limited insulin production remained.